GPAT Pharmaceutical Chemistry Syllabus 2021 – Get Syllabus PDF Here


Latest Applications Open 2021:

     

GPATThe National Testing Agency is shortly known as NTA, and it is conducted the GPAT 2021 Examination, which is commonly known as the Graduate Pharmacy Aptitude Test. There is many of the candidates may appear for this examination every year.

Those candidates are interested in getting admission in the medical courses, they can fill the application form of GPAT, and through this examination result, and the candidates will be eligible and go for the counseling procedure.

Here, through this article, the candidates will be able to know the complete information of GPAT  in which includes GPAT 2021 Syllabus.

GPAT Pharmaceutical Chemistry Syllabus – PDF Available

New GPAT 2021 Pharmaceutical Chemistry Syllabus is Available. Click Here to Download PDF.

Pharmaceutical Chemistry

Latest Applications For Various UG & PG Courses Open 2021:

    1. Lovely Professional University, Punjab | Admissions Open for All Courses 2021. Apply Now
    2. UPES, Dehradun | Admissions Open for All Courses 2021. Apply Now
    3. Chandigarh University, Punjab | Admissions Open for All Courses 2021. Apply Now
    4. GD Goenka, Gurgaon | Admission Open for All Courses 2021. Apply Now
    5. DIT University, Dehradun | Admission Open for All Courses 2021. Apply Now
    6. Sharda University | Admission Open all courses 2021. Apply Now
    7. Manav Rachna University, Haryana | Admission Open for all courses 2021. Apply Now

Pharmaceutical Inorganic Chemistry

Pharmaceutical Impurities: Impurities in pharmaceutical substances, sources, types & effects of impurities. Limit tests for heavy metals like lead, iron, arsenic, mercury & for chloride & sulfate as per Indian Pharmacopoeia [I. P.].

Monographs: Monograph & its importance, various tests included in monographs as per I. P. A study of the following compounds concerning their methods of preparation, assay, & pharmaceutical uses sodium citrate, calcium carbonate, copper sulfate, light & heavy kaolin, ammonium chloride & ferrous gluconate.

Isotopes: Isotopes- stable & radioactive, mode & rate of decay. Types & measurement of radioactivity. Radiopharmaceuticals & their diagnostic & therapeutic applications in pharmacy & medicine such as 125I, 32P, 51Cr, 60Co, 59Fe, 99Tc-M. Radiocontrast media, use of BaSO4 in medicine.

Dentifrices, desensitizing agents, & anticaries agents

Medicinal Chemistry

Therapeutic classes of drugs: The following topics should be dealt with covering nomenclature [including stereochemical aspects], biological activity [including side & toxic effects ], mode of action, structure-activity relationship [where ever applicable] & syntheses of reasonable molecules.

  • Dentifrices, desensitizing agents, & anticaries agents.
  • General anesthetics.
  • Local anesthetics.
  • Antiseptics, disinfectants, sterilants, & astringents.
  • Purgatives, laxatives & antidiarrhoeal agents.
  • Diagnostic agents.
  • Coagulants, anticoagulants & plasma expanders.
  • Drug metabolism

Introduction to drug metabolism based on the functional groups.

Various classes of therapeutic agents: A detailed study of the following classes with respect to drug nomenclature, classification, physicochemical properties, mode of action [MOA], structure-activity relationships [SAR], wherever applicable, synthesis of simple & prototype molecules, drug metabolism, therapeutic uses & side effects. Drug resistance, wherever applicable, should be covered in respective classes of drugs.

  • Antiamoebic agents.
  • Anthelmintic agents.
  • Antibacterial sulpha drugs [only].
  • Quinolone antibacterials.
  • Antimycobacterial drugs.
  • Antifungal agents.
  • Antiviral agents, including HIV & anti-HIV drugs.
  • Thyroid & antithyroid drugs.
  • Antiallergic agents.
  • Antiulcer agents & Proton Pump Inhibitors.
  • Hypoglycemic agents.
  • Antimalarials

Different classes of therapeutic drugs: A detailed study of the following courses concerning drug nomenclature, classification, physicochemical properties, mode of action [MOA], structure-activity relationships [SAR], wherever applicable, synthesis of simple & prototype molecules, drug metabolism, therapeutic uses & side effects. Drug resistance, wherever applicable, should be covered in respective classes of drugs.

  • Sedative-hypnotics
  • Antiepileptic agents.
  • Neuroleptics
  • Anti-anxiety drugs.
  • Diuretics.
  • Penicillins, cephalosporins & other beta-lactam antibiotics like imipenem & aztreonam. Beta-lactamase inhibitors,, such as clavulanic acid & sulbactam. Chloramphenicol. Tetracyclines. Aminoglycoside antibiotics. Macrolide antibiotics. Lincomycins. Polypeptide antibiotics. Anticancer antibiotics.
  • Corticosteroids [gluco- & mineralocorticoids] & anti-inflammatory steroids. Sex steroids. Male & female contraceptive agents. Anabolic steroids. Anticancer agents.

Different Classes of Therapeutic Drugs: A detailed study of the following classes concerning drug nomenclature, classification, physicochemical properties, mode of action [MOA], biosynthesis, structure-activity relationships [SAR], wherever applicable, synthesis of simple & prototype molecules, drug metabolism, therapeutic uses & side effects. Drug resistance, wherever applicable, in respective classes of drugs.

  • Narcotic [centrally acting] analgesics [analgetics]. Morphine & all its structural modifications [peripheral & nuclear]. Narcotic agonists & antagonists [dual & pure]. Non-narcotic analgesics [NSAIDS]. Difference between narcotic & non­narcotic agents.
  • Adrenergic drugs. Neurotransmitters & their role. General & specific adrenergic agonists & antagonists [up to alpha-2 & beta-2 only].
  • Cholinergic agents. Muscarinic & nicotinic cholinergic agonists & antagonists [up to M2 & N2]. Neuronal [transmission] blockers.
  • Drugs used in neuromuscular disorders. Drugs used in the treatment of Parkinson’s disease. Central & peripheral muscle relaxants.
  • Hypertensive, antihypertensive, & antianginal agents.
  • Prostaglandins, prostacyclins, & thromboxanes. Their biochemical role, biosynthesis, & inhibitors.
  • Introduction to the quantitative structure-activity relationship. [QSAR]. Linear free energy relationship. Hammett’s equation. Use of substituent constants such as n, o, Es, & physicochemical parameters such as pKa, partition coefficient, Rm, chemical shifts, molar refractivity, simple & valance molecular connectivity to indicate electronic effects, lipophilic effects, & steric effects. Introduction, methodology, advantages & disadvantages/limitations of Hansch analysis.
  • Asymmetric synthesis. Chirality, chiral pool, sources of various naturally available chiral compounds. Eutomers, distomers, eudismic ratio. Enantioselectivity & enantiospecificity. Enantiomeric & diastereomeric excess. Prochiral molecules. Asymmetric synthesis of captopril & propranolol.
  • Combinatorial chemistry. Introduction & basic terminology. Databases & libraries. Solid-phase synthesis technique. Types of supports & linkers, Wang, Rink, & dihydropyran, derivatized linkers. Reactions involving these linkers. Manual parallel & automated parallel synthesis. Houghton’s tea bag method, micromanipulation, recursive deconvolution. Mix & split plan for the integration of tripeptides. Limitations of combinatorial synthesis. Introduction to throughput screening.

Also, Check Below-

Latest Applications For Various UG & PG Courses Open 2021:

    1. Lovely Professional University, Punjab | Admissions Open for All Courses 2021. Apply Now
    2. UPES, Dehradun | Admissions Open for All Courses 2021. Apply Now
    3. Chandigarh University, Punjab | Admissions Open for All Courses 2021. Apply Now
    4. GD Goenka, Gurgaon | Admission Open for All Courses 2021. Apply Now
    5. DIT University, Dehradun | Admission Open for All Courses 2021. Apply Now
    6. Sharda University | Admission Open all courses 2021. Apply Now
    7. Manav Rachna University, Haryana | Admission Open for all courses 2021. Apply Now

Pharmaceutics

Pharmacology

If you any queries regarding GPAT Pharmaceutical Chemistry Syllabus 2021, you can ask your question leave comments below.

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  1. Sneha Kundu says:

    Please send me the gpat syllabus (each and every subject)

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